郝大程

2019年01月15日 00:00 浏览:3794
  
 
姓  名 : 郝大程             
职  称 : 教      
学术职硕士生导师                             
所学专业生物化工  
研究方向资源和环境生物技术,生化工程           
联系电话 :13998442860                        
Email      
hao@djtu.edu.cn         haodc@126.com                                              
学习工作经历
2008/04-2010/01,中国医科院药用植物研究所中草药物质基础与资源利用教育部重点实验室,博士后
2004/09-2008/01,中科院大连化学物理研究所药用资源开发组,工学博士
2000/07 - 2002/12,新加坡国立大学医学院,科学硕士
1989/09-1994/07,西安交通大学医学院,学士
2019.11至今,大连交通大学,环境化工学院/环境科学与工程系,教授
2011/07-2019/10 ,大连交通大学,环境化工学院/生物技术研究所,副教授
其中2012.11-2013.10,英国John Innes Centre,代谢生物学系,访问学者(CSC资助)
2008/03-2011/06, 大连交通大学,环境化工学院/生物技术研究所,讲师
2003/02-2004/08,香港科技大学生物系,研究助理
承担项目情况
主持或参加的纵横向课题
1.国家自然科学基金面上项目(与中科院应用生态研究所合作),秸秆覆盖下土壤线虫-微生物碳通道对微生物残留物积累的调控机制,2020-2023,13.4万元,在研,主持
2.辽宁省教育厅科研项目,基于仿生装置和根际的土壤有机物污染原位自持修复,2019.07-2022.07, 4万元,在研,主持
3.辽宁省自然科学基金,20180550190,土壤PAH污染的仿生修复和根际修复研究,2018.07-2021,在研,主持.
4.辽宁省研究生教育教学改革研究计划项目,毒物代谢酶细胞色素P450 2J2研究,2016.07-2018.12,结题,主持
5.辽宁省自然科学基金,2015020663 辽宁省毛茛科药用植物亲缘学研究初探2015.07-2017.12,结题,主持  ,,
6.教育部48批留学回国人员科研启动基金,20141685,红豆杉紫杉烷糖苷生物合成调控,2015,3万元,结题,主持
7.国家留学基金,201208210122,鼠尾草属药用植物的转录组和代谢组研究,2012.11-2013.10,已结题,主持
8.2批中国博士后科学基金特别资助,200902069,红豆杉基因组和转录组研究,2009.10-2010.09,10万元,已结题,主持
9.辽宁省教育厅科研项目,2009A120,海胆毒物代谢酶基因研究,2009.09-2011.08,2万元,已结题,主持
10.44批中国博士后科学基金一等资助,20080440019,贝母属药用植物的化学分类和分子分类研究,2008.10-2009.09,5万元,已结题,主持

发表论文著作情况
Gao R(undergraduate), Hao DC(co-first author & corresponding author), Hu
WL, Song S, Li SY, Ge GB. Transcriptome profile of polycyclic aromatic
hydrocarbon-degrading fungi isolated from Taxus rhizosphere. Curr Sci. 2019;116(7): 1218-28
 
Hao DC. Ranunculales medicinal plants:
Biodiversity, chemodiversity and pharmacotherapy. London: Elsevier/Academic
Press 2018 ISBN: 978-0128142325
 
Hao DC, Xiao PG, Liu C(undergraduate). Traditional
Tibetan medicinal plants: a highlighted resource for novel therapeutic
compounds. Future Med Chem. 2018; 10(21): 2537
55
 
Ma HY(graduate student), Yang JD, Hou J, Zou LW, Jin Q, Hao DC (co-corresponding
author), Ning J, Ge GB, Yang L. Comparative metabolism of DDAO benzoate in
liver microsomes from various species. Toxicol In Vitro. 2017. 44:280-286
 
Hao DC, Xiao PG. 药用植物亲缘学导论An Introduction of Plant Pharmacophylogeny.Beijing: 化学工业出版社Chemical Industry Press; 1 edition (Jan.
2017) ISBN:978-7-122-28201-9 full text in Chinese 2019
大连市科学著作奖二等奖
 
Hao DC, Song SM, Mu J, Hu WL, Xiao PG.Unearthing
microbial diversity of Taxus rhizosphere via MiSeq high-throughput amplicon
sequencing and isolate characterization. Sci Rep. 2016;6:22006
 
Hao DC, Ge GB, Xiao PG, Wang P, Yang L. Drug Metabolism and Pharmacokinetic
Diversity of Ranunculaceae Medicinal Compounds.
Curr Drug Metab. 2015;16(4):294-321
 
Hao DC, Xiao PG, Ma HY, Peng Y, He CN. Mining chemodiversity from biodiversity:
pharmacophylogeny of medicinal plants of Ranunculaceae.

Chin J Nat Med.
2015;13(7):507-20
 
Hao DC, Gu XJ, Xiao PG. Medicinal plants: Chemistry, biology and omics
[M].Oxford: Elsevier-Woodhead, 2015. ISBN 9780081000854

专著2018大连市科学著作奖三等奖
 
Hao DC, Chen SL, Osbourn A, Kontogianni VG, Liu LW, Jordán MJ. Temporal transcriptome changes induced
by methyl jasmonate in Salvia sclarea. Gene. 2015; 558(1):41-53
 
Hao DC, Xiao PG, Liu M, Peng Y, He CN. Pharmaphylogeny vs. pharmacophylogenomics:
molecular phylogeny, evolution and drug discovery.
Yao Xue Xue Bao. 2014;49(10):1387-94
 
Hao DC, Xiao PG. Network pharmacology: a Rosetta Stone for traditional Chinese
medicine. Drug Dev Res. 2014; 75(5):299-312
 
Hao DC, Xiao B, Xiang Y, Dong XW, Xiao PG. Deleterious nonsynonymous single nucleotide
polymorphisms in human solute carriers: the first comparison of three
prediction methods.
Eur J Drug Metab Pharmacokinet. 2013;38(1):53-62
 
Hao DC, Gu XJ,Xiao PG, et al. Chemical and biological research of Clematis medicinalresources [J]. Chin Sci Bull, 2013, 58: 1120.
 
Hao DC, Yang L,Xiao PG, Liu M. Identification of Taxus microRNAs and their targets with
high-throughput sequencing and degradome analysis. Physiol Plant. 2012;

146(4):388-403
 
Hao DC, Ma P, Mu
J, Chen SL, Xiao PG, Peng Y, Huo L, Xu L, Sun C. De novo characterization of
the root transcriptome of a traditional Chinese medicinal plant Polygonum
cuspidatum
. SciChinaLife Sci. 2012; 55(5):452-66
 
Hao DC, Ge GB,
Xiao PG, Zhang Y, Yang L. The first insight into the tissue specific taxus
transcriptome via Illumina second generation sequencing. PLoS One.
2011;6(6):e21220
 
专利
Hao DC, Song SM(graduate student), Hu WL. 发明专利授权CN201510411623.2一种产漆酶真菌菌株的分离优化方法及应用(Isolating laccase-producing fungal strains from Taxus rhizosphere,
their optimization, and applications in dye decolorization). 2018. Patent no. of


the fungal strain
CCTCC M 2014543
Hao DC, Hu WL(graduate student), Song
SM,Zhu XH.
发明专利授权CN201510411700.4一种红豆杉根际多环芳烃降解菌的筛选方法及应用(Screening polycyclic aromatic hydrocarbon-degrading fungi from
Taxus rhizosphere and their applications). 2018. Patent no. of the fungal
strain
CCTCC M 2014542
Hao DC,Men YL(undergraduate).
CN201822059291.8
一种基于人工智能的实时远程动态立体投影装置A real-time remote dynamic stereo projection device based on
artificial intelligence
,实用新型专利,授权2019
Men YL(undergraduate), Hao DC.
CN201821846282.7
日晷式太阳追踪器Sundial sun tracker,实用新型专利,授权2019
社会兼职
学术期刊编委:生物技术通报,Chinese Herbal Medicines(核心期刊)BMC
Complementary and Alternative Medicine, Pakistan Journal of Botany (SCI)
大连市科技局评审专家
获奖情况
11年省自然科学学术成果二等奖一项(2011-LNL1150)
12年省自然科学学术成果二等奖一项(2012-LNL0006)
14年大连市自然科学优秀学术论文一等奖(2014-19)和省自然科学学术成果三等奖一项(2014-LNL0003)