张翼

2012年09月05日 00:00 浏览:1818
姓  名       张翼                              
职  称       副教授                              
学术职衔    硕士生导师
荣誉称号     尚无
所学专业       海洋天然药物化学                                                
研究方向       海洋真菌及厌氧微生物生物活性物质;重要药理靶酶的海
                      藻来源抑制剂的筛选;海藻化学、生物农药等
联系电话       13372870366;18911573816;
                      0411-84109382                                                          
Email              hubeizhangyi@163.com 
 
欢迎研究生报考!
详见学校主页\科学研究\科研机构中资源与环境生物技术研究所网页:
http://202.199.128.29/org22/cn/_infolist/info_3.asp?f_menu_id=609&f_id=114                      
 
学习工作经历
1997 年9 月至2001年7 月   中国海洋大学海洋生物学专业,获理学学士学位
2001 年9 月至2004年7 月   中国科学院海洋研究所海洋生物学专业天然药物化学方向,获理学硕士
                                                         学位
2004 年9 月至2007年7 月   中国科学院海洋研究所海洋生物学专业天然药物化学方向,获理学博士
                                                         学位
2007 年7 月至今    大连交通大学环境与化学工程学院,历任资源与环境生物技术研究所海洋生物制
                 药组组长、副教授、生物技术(化工与制药)教研室主任、大连理工大学化学
                 工程与技术博士后流动站生物化工在职博士后
2011 年7 月    获国家公派赴德国留学访问学者资格 
 
承担项目情况
1、鲨鱼鳃部共附生真菌抗肿瘤活性化合物的研究,国家自然科学基金,2010.1~2012.12,18万元,
      题负责人
2、三株大连潮间带海洋共附生真菌抗菌抗肿瘤活性成分的研究,大连市科学技术基金,
      2009.1~2010.12,5万元,课题负责人
3、大气压低温等离子体对海洋药源真菌的生物效应,第五十批中国博士后科研基金面上项
      目一等资助,2011.3~2013.3, 5万元,课题负责人
4、两株大连海域共附生海洋真菌抗肿瘤活性物质的研究,中国科学院实验海洋生物学重点实验室开
      放基金,2010.1~2011.12,2万元,课题负责人
5、海洋生物鳃部共附生真菌资源及其生物活性的研究,大连交通大学大学生课外科技创新基金,
      2010.1-2010.12,0.15万元,课题负责人(指导教师)
6、海洋厌氧光合细菌和硫酸盐还原细菌中活性先导化合物的研究,国家863高技术计划,
       2007.1~2009.12,100万元,参与承担人
7、海洋红树林植物黄槿内生真菌抗肿瘤活性成分研究,国家自然科学基金,2008.1~2010.12,28万
      元,参与承担人
 
部分已发表论文著作情况
 
1. Yi Zhang, Jun Mu, Xiaojie Gu, et al. Broad-Spectrum Antimicrobial Epiphytic and   Endophytic Fungi
    from Marine Organisms: Isolation, Bioassay and Taxonomy.  Marine Drugs. 2009, 7(2): 97–112.
2.Yi Zhang, Xiao-Ming Li, Bin-Gui Wang. Nigerasperones A-C, New Monomeric and Dimeric Naphtho-γ-
   pyrones from a Marine Alga-derived Endophytic Fungus Aspergillus niger EN-13. Journal of
   Antibiotics. 2007, 60(3): 204–210.
3.Yi Zhang, Song Wang, Xiao-Ming Li, Chuan-Ming Cui, Chao Feng, Bin-Gui Wang. Sphingolipids with
   previously unreported 9-methyl-C20-sphingosine moiety from algous endophytic fungus Aspergillus
   niger. Lipids. 2007,42,759–764.
4.Yi Zhang, Xiao-Ming Li, Bin-Gui Wang. Ergosterimide, a new steroid of natural Diels-Alder adduct, and
   other related steroids from the marine algal-derived endophytic fungus Aspergillus niger EN-13.
   Steroids. 2007,72, 723–727.
5.Yi Zhang, Xiao-Ming Li, Yan Feng, Bin-Gui Wang. Phenethyl-a-pyrone derivatives and cyclodipeptides
    from a marine algous endophytic fungus Aspergillus niger EN–13. Natural Product Research, 2010, 24
    (11), 1036-1043.
6.Yi Zhang, Xiao-Ming Li, Bin-Gui Wang. A New Naphthoquinoneimine Derivative from the Marine Algal-
   derived Endophytic Fungus Aspergillus niger EN-13. Chin. Chem. Lett. 2007, 18, 951–953.
7.Yi Zhang, Jun Mu, Zhen Guo, Song Yan, Hongli Lü. Abundant novel secondary metabolites from a
   marine algous endophytic fungus and their bioactivity. J. Biotech, 2008, 136S, S599.
8.Yi Zhang, Jun Mu, Rongli Zhou, Zhen Guo, Zeping Xie, and Binghua Jiao. Antimicrobial constituents of
   a marine sulfate-reducing bacterium SRB-22. J. Biotech, 2008, 136S, S600.
9.张翼, 李晓明, 王斌贵. 两株曲霉属海藻内生真菌代谢产物及生物活性研究. 有机化学, 2007, 27
   (Suppl.), 440.
10.张翼,谢则平,王晓亮,穆军. 海洋光合细菌PSB-11抗菌活性成分的初步研究. 2008年全国海洋生
     物技术与创新药物学术会议论文集, 89-95.
11.张翼, 李晓明, 王斌贵. 海藻内生真菌Aspergillus niger EN-13中的萘并吡喃酮类次生代谢产物. 2006
     年全国海洋生物技术与海洋药物学术会议论文集, 576–580.
12.张翼, 冯妍, 李晓明, 王斌贵. 海藻组分抑制乙酰胆碱酯酶活性研究. 海洋与湖沼, 2005, 36(5): 459–
     464.
13.张翼, 陈昌祥, 李晓明, 王斌贵.红藻海头红脂溶性化学成分研究. 中草药, 2006, 37(11): 1626–1627.
14.张翼, 李晓明, 王斌贵.海藻生物活性物质研究的回顾与展望. 世界科技研究与发展, 2005, 27(5): 56–
     63.
 
参加会议情况
2003.11 参加亚洲药用植物、香料与其他天然产物学术大会
2005.9  担任科技部“海洋生物技术与海洋药物国际培训班”组织联系人
2006.8  参加全国海洋生物技术与海洋药物学术会议
2006.10 担任科技部“海洋生物技术与海洋生物制品国际培训班”组织联系人
2007.9  参加全国海洋药物高级研讨会
2008.10 参加第十三届国际生物技术大会暨展览会
2008.12 参加全国海洋生物技术与创新药物学术研讨会暨海洋生物技术高级论坛
 
获奖情况
尚无
 
社会兼职
尚无
 
 
 
 
 
 
 
 
 
 
Name: Yi Zhang
Academic Title: Associate Professor
Academic Rank: Master's Tutor
Title of Honor: None
Speciality: Marine Natural Pharmaceutical Chemistry
Focus of Research: Marine fungi and anaerobic microorganisms derived
                             bioactive substances; Screening of Inhibitors of
                             important target enzymes from marine seaweeds; Seaweed
                             Chemistry; Bio-pesticides,etc.
Tel: 13372870366; +86-411-84109382
 
Education and Work Experiences
1997.9 to 2001.7   Department of Maine Biology, Ocean University of China; Bachelor's
                              Degree in Philosophy
2001.9 to 2004.7  Group of marine natural pharmaceutical chemistry, Key laboratory of
                             Experimental Marine Biology, Institute of Oceanology, the Chinese
                             Academy of Sciences; Master's Degree in Philosophy
2004.9 to 2007.7  Group of marine natural pharmaceutical chemistry, Key laboratory of
                             Experimental Marine Biology, Institute of Oceanology, the Chinese
                             Academy of Sciences; Ph D
2007.7 to now   School of Environmental and Chemical Engineering, Dalian Jiaotong
                          University; work as a lecturer and the leader of Marine Pharmaceutical Group of
                          Institute of  Biotechnology in Resource and Environment
 
Project Development
1、Research on antitumor bioactive compounds of symbiotic and adnascent fungal strains
      from shark's gill, sponsored by the Natural Science Fund of China, 2010.1~2012.12,  
      180,000 RMB Yuan, the topic responsible person
2、The research on the antimicrobial and antitumor bioactive constituents of three symbiotic
      and adnascent fungal strains collected form the Dalian intertidal zones, sponsored by the
      Fund of Science and Technology of Dalian City, 2009.1~2010.12,50,000 RMB Yuan,
      the topic responsible person
3、The research of the bioactive leading compounds from the marine anaerobic
      photosynthetic bacteria and sulfate-reducing bacteria, the National 863 High-Tech Project
      of China, 2007.1~2009.12, 1,000,000 RMB Yuan, participant
4、Investigation of antitumor constituents of the endophytic fungi isolated from marine
      mangrove plant Hibiscus tiliaceus Linn., the National Natural Science Fund of China,
      2008.1~2010.12, 280,000 RMB Yuan, participant
 
Publications              
1. Yi Zhang,Jun Mu, Xiaojie Gu, et al. Broad-Spectrum Antimicrobial Epiphytic  
    andEndophytic Fungi from Marine Organisms: Isolation, Bioassay and Taxonomy. 
    Marine Drugs. 2009, 7(2): 97–112.
2. Yi Zhang, Xiao-Ming Li, Bin-Gui Wang. Nigerasperones A-C, New Monomeric and 
    Dimeric Naphtho-γ-pyrones from a Marine Alga-derived Endophytic Fungus Aspergillus
    niger EN-13. Journal of Antibiotics. 2007, 60(3): 204–210.
3. Yi Zhang, Song Wang, Xiao-Ming Li, Chuan-Ming Cui, Chao Feng, Bin-Gui Wang.
    Sphingolipids with previously unreported 9-methyl-C20-sphingosine moiety from algous
    endophytic fungus Aspergillus niger. Lipids. 2007,42,759–764.
4. Yi Zhang, Xiao-Ming Li, Bin-Gui Wang. Ergosterimide, a new steroid of natural Diels-
    Alder adduct, and other related steroids from the marine algal-derived endophytic fungus
    Aspergillus niger EN-13. Steroids. 2007,72, 723–727.
5. Yi Zhang, Xiao-Ming Li, Bin-Gui Wang. A New Naphthoquinoneimine Derivative from the
    Marine Algal-derived Endophytic Fungus Aspergillus niger EN-13. Chin. Chem. Lett.
    2007, 18, 951–953.
6. Yi Zhang, Jun Mu, Zhen Guo, Song Yan, Hongli Lü. Abundant novel secondary
    metabolites from a marine algous endophytic fungus and their bioactivity. J. Biotech, 2008,
    136S, S599.
7. Yi Zhang, Jun Mu, Rongli Zhou, Zhen Guo, Zeping Xie, and Binghua Jiao. Antimicrobial
    constituents of a marine sulfate-reducing bacterium SRB-22. J. Biotech, 2008, 136S, S600.
8. Yi Zhang, et al. The investigation of the inhibitory activity of marine algae fractions against
    AchE, Chinese Journal of Oceanology and Limnology, 2005, 36(5): 459–464.
9. Yi Zhang, et al. The research of the fat-soluble constituents of the red alga Plocamium
    telfairiae Harv., Chinese Journal of Traditional Herbal Medicines, 2006, 37(11): 1626–
   1627.
10. Yi Zhang, et al. Review and prospect of seaweed derived bioactive substances, World
      Sci-Tech R & D, 2005, 27(5): 56–63.
 
Awards
None
Professional Memberships and other positions
None